From the very few characters I recognize, I guess it's about the meme itself, as the box in the first panel reads "A.D.2010", when "yukkuri" might not be popular anymore. Just a guess though. *summoning dear translators*
yes, the thread in the panel says "yukkuri shiteitte ne!" "oh wow, a nostalgic blast from the past" "yukkuri isn't nostalgic! yukkuri is still living strong!"
the rest of it is how no one can see yukkuri anymore because she's forgotten.