Castration is useless in Alices, they can grow PeniPenis in any spot of the skin and probably the knockout pill and the Viayugra dose is tailored for the metabolism of each Yukkuri. An example, Patchoulis and Youmus have very soft skin, so Viayugra must have a lower concentration in order to avoid breaking the PeniPeni skin by excessive stretching. Another example could be the dose of anaesthetic for Patchouli types, the dose for healthy Yukkuris might induce them a permanent coma.